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Bupropion

Bupropion is an atypical antidepressant that primarily acts as a norepinephrine-dopamine reuptake inhibitor. It is used for the treatment of depression and to assist with smoking cessation. The substance primarily affects the dopamine and norepinephrine transporters without significantly impacting serotonin receptors. Side effects may include seizures in case of overdose, making careful use important.

Antidepressiva
Antidepressiva
Dopamintransporter
Noradrenalintransporter

Mechanism of Action

  • NDRI
Detailed mechanism of action

Names / Identifiers

IUPAC: Bupropion

Mechanism of Action

Bupropion wirkt als Hemmer der Wiederaufnahme von Dopamin und Noradrenalin, was zu einer Erhöhung der Verfügbarkeit dieser Neurotransmitter im synaptischen Spalt führt.

Effects

Antidepressiv
Stimmungsaufhellend
Appetithemmend
Energiesteigernd
Konzentrationsfördernd

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 weeks
NotesEffect may vary from person to person.
Onset1-2 weeks
Total24 hours
After Effectsunknown

Risks & Warnings

Warnings

  • Epilepsy
  • Anorexia
  • Bulimia

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Schlaflosigkeit, Mundtrockenheit und erhöhter Blutdruck.

Safer Use

  • Start at a low dose.
  • Conduct regular medical check-ups.

Harm reduction tips do not replace medical advice.

Known Interactions

  • MAO inhibitors
  • Antidepressants
  • Alcohol

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesIn vielen Ländern ist Bupropion als Medikament zur Behandlung von Depressionen und zur Unterstützung bei der Raucherentwöhnung zugelassen.

Not legal advice. Status may change.