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2-(tert-butylamino)-1-(3-chlorophenyl)propan-1-one
Bupropion is an atypical antidepressant that primarily acts as a norepinephrine-dopamine reuptake inhibitor. It is used for the treatment of depression and to assist with smoking cessation. The substance primarily affects the dopamine and norepinephrine transporters without significantly impacting serotonin receptors. Side effects may include seizures in case of overdose, making careful use important.
Class
Antidepressiva
Pharmacological context
Mechanism
Bupropion wirkt als Hemmer der Wiederaufnahme von Dopamin und...
Short read on known pharmacology
Interactions
3 documented
Curated visible combinations
Risk theme
Interpret risks carefully
Condensed from structured notes
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Designations
IUPAC: Bupropion
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Synapedia Evidence
Effects & Pharmacology translation in progress
English prose is being expanded. The German version currently has more detail.
Reported range 200 mg
Total duration 24 hours
Oral
| Tier | Dosage |
|---|---|
| Light | 100 mg |
| Reported | 200 mg |
| Strong | 400 mg |
Oral
Onset
1–2 weeks
Peak
4–6 weeks
Total duration
24 hours
Avoid uncertain dosage claims and do not infer numbers when data is unclear.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Mögliche Nebenwirkungen umfassen Schlaflosigkeit, Mundtrockenheit und erhöhter Blutdruck.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Caution-level interaction risk
Detailed interaction narrative is still being translated. This row shows the available risk level and data provenance only.
Caution-level interaction risk
Detailed interaction narrative is still being translated. This row shows the available risk level and data provenance only.
Caution-level interaction risk
Detailed interaction narrative is still being translated. This row shows the available risk level and data provenance only.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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