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Substance Comparison
Bupropion lasts considerably longer at around 24 hours, while α-PHP clocks in at roughly 6 hours. α-PHP stands out with markedly stronger addiction risk. In terms of stimulation, α-PHP scores notably higher. In terms of body load, α-PHP scores notably higher.
Despite belonging to different classes, these substances share receptor activity at DAT and NET, which may produce overlapping effects.
Insights
α-PHP has significantly higher addiction risk
α-PHP has notably higher stimulation
α-PHP has notably higher body load
Bupropion has somewhat higher sedation
| α-PHP | Bupropion | |
|---|---|---|
| Class | Stimulanzien | Antidepressiva |
| Risk Level | high | low |
| Mechanisms | DAT-Inhibitor, NET-Inhibitor | DAT-Inhibitor, NET-Inhibitor |
| Receptors | DAT, NET | DAT, NET |
| Effects | Gesteigerte Wachheit und Konzentration, Erhöhter Antrieb und Motivation, Euphorie und gesteigertes Selbstvertrauen, Verminderte Müdigkeit, Gesteigerte körperliche Leistungsfähigkeit | Antidepressiv, Stimmungsaufhellend, Appetithemmend, Energiesteigernd, Konzentrationsfördernd |
| Evidence | unknown | unknown |
Alpha-Pyrrolidinohexiophenone wirkt hauptsächlich als Hemmer der Wiederaufnahme von Dopamin, Noradrenalin und Serotonin, was zu einer erhöhten Verfügbarkeit dieser Neurotransmitter im synaptischen Spalt führt.
Bupropion wirkt als Hemmer der Wiederaufnahme von Dopamin und Noradrenalin, was zu einer Erhöhung der Verfügbarkeit dieser Neurotransmitter im synaptischen Spalt führt.
Safer-use data available on substance page
Safer-use data available on substance page
Evidence: unknown · Sources: 3
Evidence: unknown · Sources: 3