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Substance Comparison
Bupropion lasts considerably longer at around 24 hours, while NEP (N-Ethylpentedron) clocks in at roughly 5 hours. NEP (N-Ethylpentedron) stands out with markedly stronger addiction risk. In terms of stimulation, NEP (N-Ethylpentedron) scores notably higher. In terms of body load, NEP (N-Ethylpentedron) scores notably higher.
Despite belonging to different classes, these substances share receptor activity at DAT and NET, which may produce overlapping effects.
Insights
NEP (N-Ethylpentedron) has significantly higher addiction risk
NEP (N-Ethylpentedron) has notably higher stimulation
NEP (N-Ethylpentedron) has notably higher body load
Bupropion has somewhat higher sedation
| Bupropion | NEP (N-Ethylpentedron) | |
|---|---|---|
| Class | Antidepressiva | Stimulanzien |
| Risk Level | low | high |
| Mechanisms | DAT-Inhibitor, NET-Inhibitor | DAT-Inhibitor, NET-Inhibitor |
| Receptors | DAT, NET | DAT, NET |
| Effects | Antidepressiv, Stimmungsaufhellend, Appetithemmend, Energiesteigernd, Konzentrationsfördernd | Euphorie, Erhöhte Wachsamkeit, Steigerung der Energie, Geselligkeit, Appetithemmung |
| Evidence | unknown | unknown |
Bupropion wirkt als Hemmer der Wiederaufnahme von Dopamin und Noradrenalin, was zu einer Erhöhung der Verfügbarkeit dieser Neurotransmitter im synaptischen Spalt führt.
DAT inhibitor; SERT inhibitor
Safer-use data available on substance page
Safer-use data available on substance page
Evidence: unknown · Sources: 3
Evidence: unknown · Sources: 4