Synapedia

Translated automatically – community improvements welcome.

IL-6001

Trimipramine is a tricyclic antidepressant with sedative properties, primarily acting through the inhibition of norepinephrine and serotonin reuptake. Additionally, it blocks histamine and muscarinic acetylcholine receptors, contributing to its sedative effects. It is mainly used for the treatment of depression and sleep disorders. The side effect profile includes anticholinergic effects and sedation, necessitating a careful benefit-risk assessment.

Antidepressiva
Antidepressiva
Serotonin-Transporter
Noradrenalin-Transporter
Histamin-H1-Rezeptor
Muskarinische Acetylcholinrezeptoren

Mechanism of Action

  • NET inhibitor
  • SERT inhibitor

Names / Identifiers

IUPAC: Trimipramine

trimipramine
739-71-9
Trimeprimine
Trimeproprimine
Sapilent
beta-Methylimipramine
Trimeprimina
Trimipramina
Trimipraminum
7162 RP

Mechanism of Action

Trimipramine wirkt hauptsächlich als Hemmer der Wiederaufnahme von Serotonin und Noradrenalin, was zu einer Erhöhung der Verfügbarkeit dieser Neurotransmitter im synaptischen Spalt führt.

Effects

Antidepressiv
Anxiolytisch
Sedierend
Schmerzlindern
Antihistaminisch
Anticholinerg

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak2-4 weeks
NotesThe effect may build up over several weeks.
Onset1-2 weeks
Total24 hours
After EffectsVariable

Risks & Warnings

Warnings

  • Acute myocardial infarction
  • Pregnancy
  • Breastfeeding

Known Risks

  • medium
  • Trimipramine kann Nebenwirkungen wie Schläfrigkeit, Mundtrockenheit und Gewichtszunahme verursachen.

Safer Use

  • Regular medical monitoring.
  • Avoidance of alcohol and other sedating substances.

Harm reduction tips do not replace medical advice.

Known Interactions

  • MAO inhibitors
  • other antidepressants
  • alcohol

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesTrimipramine ist in vielen Ländern als verschreibungspflichtiges Medikament eingestuft.

Not legal advice. Status may change.