Synapedia

Translated automatically – community improvements welcome.

Dyna-zina

Imipramine is a tricyclic antidepressant that primarily works by inhibiting the reuptake of serotonin and norepinephrine. It also has antagonistic effects at various receptors, which can lead to side effects. The substance is used to treat depression and other affective disorders. Due to its side effect profile and toxic potential, careful medical monitoring is required.

Antidepressiva
Antidepressiva
Serotonin-Rezeptoren
Noradrenalin-Rezeptoren
Histamin-Rezeptoren
Muskarinische Acetylcholinrezeptoren

Mechanism of Action

  • NET inhibitor
  • SERT inhibitor

Names / Identifiers

IUPAC: Imipramine

imipramine
50-49-7
Melipramine
Antideprin
Berkomine
Imidobenzyle
Dimipressin
Melipramin
Dynaprin
Intalpram

Mechanism of Action

Imipramin wirkt hauptsächlich durch die Hemmung der Wiederaufnahme von Serotonin und Noradrenalin, was zu einer Erhöhung der Konzentration dieser Neurotransmitter im synaptischen Spalt führt.

Effects

Antidepressiv
Anxiolytisch
Sedierend
Anticholinerg
Hypnotisch
Stimmungsaufhellend
Schmerzlindern

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 weeks
NotesThe effect may build up over several weeks.
Onset1-3 weeks
Total24 hours
After EffectsVariable

Risks & Warnings

Warnings

  • Acute myocardial infarction
  • Pregnancy
  • Concurrent use of MAO inhibitors

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Schläfrigkeit, Mundtrockenheit und Gewichtszunahme.

Safer Use

  • Regular medical monitoring
  • Slow dose adjustment
  • Avoidance of alcohol

Harm reduction tips do not replace medical advice.

Known Interactions

  • MAO inhibitors
  • other antidepressants
  • alcohol

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesImipramin ist in vielen Ländern als verschreibungspflichtiges Medikament eingestuft.

Not legal advice. Status may change.