Translated automatically – community improvements welcome.
Tramadol
Tramadol is a synthetic opioid with analgesic effects, acting both as a μ-opioid receptor agonist and as a reuptake inhibitor of serotonin and norepinephrine. It is used for the treatment of moderate to moderately severe pain. Due to its mechanisms of action, there is a risk of dependence, serotonin syndrome, and other side effects. The combination with other serotonergic substances should be avoided.
Mechanism of Action
- serotonin reuptake inhibitor
- μ-opioid receptor agonist
Names / Identifiers
IUPAC: Tramadol
Mechanism of Action
Tramadol wirkt als Analgetikum, indem es die Wiederaufnahme von Serotonin und Noradrenalin hemmt und an μ-Opioidrezeptoren bindet.
Effects
Effects described from scientific sources. Individual experiences vary.
Dosage
Individual sensitivity varies. Not a dosage recommendation.
Duration
Risks & Warnings
Warnings
- Acute respiratory depression
- severe liver or kidney disease
- epilepsy or seizure tendency
Known Risks
- medium
- Tramadol kann abhängig machen und hat ein Risiko für Überdosierung.
Safer Use
- Start at a low dose.
- Avoid polydrug use with other CNS depressants.
- Regular medical monitoring.
Harm reduction tips do not replace medical advice.
Known Interactions
- MAO inhibitors
- other opioids
- SSRIs/SNRIs
This list is not exhaustive. Interactions can have unpredictable effects.
Legal Status
Not legal advice. Status may change.
Entdecken
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