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Fentanyl

Fentanyl is a highly potent synthetic opioid that is primarily used as an analgesic and anesthetic. It acts as an agonist at the μ-opioid receptor and has a high potential for addiction and dependence. Due to its strong effects, there is a significant risk of respiratory depression and overdose. Fentanyl is used under medical supervision but is also associated with a high risk of abuse and death.

Opioide
High risk

Mechanism of Action

  • μ-opioid receptor agonist
Detailed mechanism of action

Names / Identifiers

IUPAC: Fentanyl

fentanyl
Phentanyl
Fentanil
Fentanest
437-38-7
Duragesic
Sublimase
Fentanylum
Durogesic
Fentanila

Mechanism of Action

Fentanyl acts as an agonist at μ-opioid receptors in the central nervous system, leading to significant pain relief. It also affects the reward system, contributing to a high potential for dependence.

Effects

Strong pain relief
Rapid onset of action
Can be used in anesthesia
Respiratory depression
Confusion
Nausea

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at low doses, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak30-60 minutes (intravenous), 24-36 hours (transdermal)
NotesDuration of action may vary depending on dose and route of administration.
Onset1-5 minutes (intravenous), 12-24 hours (transdermal)
Total1-3 hours (intravenous), 72 hours (transdermal)
After EffectsVariable, may last several hours.

Risks & Warnings

Warnings

  • Respiratory diseases
  • severe liver or kidney diseases
  • Pregnancy

Known Risks

  • high
  • Hohe Risiken für Atemdepression, Überdosierung und Abhängigkeit.

Safer Use

  • Start at low doses
  • Monitor breathing
  • Use naloxone in case of overdose

Harm reduction tips do not replace medical advice.

Known Interactions

  • Benzodiazepines
  • Alcohol
  • other opioids

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig, Betäubungsmittel
CHVerschreibungspflichtig, Betäubungsmittel
DEVerschreibungspflichtig, Betäubungsmittel
USVerschreibungspflichtig, kontrollierte Substanz (Schedule II)
NotesFentanyl ist in vielen Ländern als Betäubungsmittel klassifiziert und unterliegt strengen Kontrollen.

Not legal advice. Status may change.

Entdecken

Gemeinsame Wirkungsmuster

Wirkungen, die Fentanyl mit verwandten Substanzen teilt.

euphorie
auch beiKratom, Amphetamin, DMT+3 weitere
schmerzlinderung
auch beiKetamin, Kratom, SSRI
übelkeit
auch bei2C-B, Ketamin, Psilocybin
verwirrtheit
auch bei2C-B, Ketamin
sedierung
auch beiKratom