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Phenobarbital

Phenobarbital is a barbiturate with sedative and anticonvulsant effects. It enhances the action of the neurotransmitter GABA at the GABA-A receptor, leading to inhibition of neuronal activity. The substance is primarily used for the treatment of epilepsy and has a moderate risk for dependence and side effects. Due to its mechanism of action, phenobarbital can lead to severe central nervous system depression in case of overdose.

Depressiva
Depressiva
GABA-A-Rezeptor

Mechanism of Action

  • GABA-A receptor agonist

Names / Identifiers

IUPAC: Phenobarbital

phenobarbital
Phenobarbitone
Luminal
Phenobarbitol
50-06-6
Fenobarbital
Nunol
Phenylethylbarbiturate
Dormiral
Gardenal

Mechanism of Action

Phenobarbital wirkt als ein langwirksames Barbiturat, das die GABA-A-Rezeptoren im zentralen Nervensystem aktiviert und dadurch die neuronale Erregbarkeit verringert.

Effects

Sedierung
Anxiolyse
Antikonvulsion
Muskelrelaxation
Hypnotische Wirkung

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak2-4 hours
NotesEffects may vary depending on dose and individual sensitivity.
Onset30-60 minutes
Total6-12 hours
After EffectsVariable, may last several hours.

Risks & Warnings

Warnings

  • Severe respiratory diseases
  • Liver diseases
  • Pregnancy

Known Risks

  • medium
  • Kann zu Abhängigkeit führen, Überdosierung ist möglich.

Safer Use

  • Start at a low dose.
  • Avoid alcohol and other depressants.
  • Regular medical check-ups.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Alcohol
  • Benzodiazepines
  • Opioids

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesIn vielen Ländern ist Phenobarbital aufgrund seines Missbrauchspotenzials reguliert.

Not legal advice. Status may change.

Entdecken

Ähnliche Substanzen

Basierend auf Substanzklasse, Rezeptoren, Wirkmechanismen und Wirkprofil.

Gemeinsame Wirkungsmuster

Wirkungen, die Phenobarbital mit verwandten Substanzen teilt.

sedierung
auch beiKratom