Synapedia
Back to substances
Deutsch|English

Translated automatically – community improvements welcome.

Fospropofol

Fospropofol is a water-soluble prodrug of Propofol that is enzymatically converted to Propofol after intravenous administration. It exerts sedative and hypnotic effects by enhancing GABAergic neurotransmission. Due to its pharmacokinetic properties, it is used in anesthesia and sedation. The substance has a moderate risk profile, particularly regarding respiratory depression and cardiovascular effects.

Depressiva
Depressiva
GABA-A Rezeptoren

Mechanism of Action

  • GABA-A receptor potentiation
Detailed mechanism of action

Names / Identifiers

IUPAC: Fospropofol

Fospropofol
258516-89-1
[2,6-di(propan-2-yl)phenoxy]methyl dihydrogen phosphate
LZ257RZP7K
Methanol, (2,6-bis(1-methylethyl)phenoxy)-, dihydrogen phosphate
DTXSID50870295
(2,6-di(propan-2-yl)phenoxy)methyl dihydrogen phosphate
fospropofolum
RefChem:141398
DTXCID20202049

Mechanism of Action

Fospropofol wirkt sedierend und hypnotisch, indem es die GABAerge Neurotransmission verstärkt.

Effects

sedierend
hypnotisch
anxiolytisch
muskelrelaxierend
schmerzlindern

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start with a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak10-15 minutes
NotesEffects may vary depending on individual response.
Onset3-5 minutes
Total15-30 minutes
After Effectsshort

Risks & Warnings

Warnings

  • Severe respiratory diseases.
  • Allergy to Propofol or related substances.

Known Risks

  • medium
  • Mögliche Atemdepression und kardiovaskuläre Effekte.

Safer Use

  • Monitoring of vital signs during use.
  • Avoiding polydrug use with other depressants.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Enhanced effects by other GABAergic substances.
  • Interactions with opioids.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesFospropofol ist in vielen Ländern nur für den Einsatz in medizinischen Einrichtungen zugelassen.

Not legal advice. Status may change.