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Zaleplon

Zaleplon is a short-acting sedative from the pyrazolopyrimidine group, primarily used for the treatment of sleep disorders. It acts as an agonist at the GABA-A receptor, thereby enhancing the inhibitory effect of the neurotransmitter GABA. Due to its short half-life, it is preferred for sleep initiation. The risk of dependence and side effects is moderate, especially with prolonged use.

Depressiva
Depressiva
GABA-A-Rezeptoren

Mechanism of Action

Names / Identifiers

IUPAC: Zaleplon

zaleplon
Sonata
151319-34-5
CL-284846
SKP-1041
ZAL-846
CL 284,846
Zaleplon civ
L846
LJC-10846

Mechanism of Action

Zaleplon wirkt als ein selektiver Agonist an den GABA-A-Rezeptoren, was zu einer verstärkten Hemmung der neuronalen Aktivität führt und somit schlaffördernde Effekte erzeugt.

Effects

Schlaffördernd
Angstlindernd
Muskelrelaxierend
Sedierend
Amnesierend

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak1-2 hours
NotesEffect may vary depending on individual metabolism.
Onset15-30 minutes
Total4-6 hours
After Effects1-2 hours

Risks & Warnings

Warnings

  • Pregnancy
  • Breastfeeding
  • Severe respiratory diseases

Known Risks

  • medium
  • Zaleplon kann zu Abhängigkeit führen und hat potenzielle Wechselwirkungen mit anderen Substanzen.

Safer Use

  • Start at a low dose.
  • Avoid alcohol and other sedatives.
  • Do not use longer than recommended.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Alcohol
  • Benzodiazepines
  • Opioids

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesZaleplon ist in vielen Ländern als Schlafmittel zugelassen.

Not legal advice. Status may change.