Translated automatically – community improvements welcome.
Promethazine
Promethazine is a first-generation antihistamine with sedative properties. It primarily acts as an H1 receptor antagonist and additionally possesses anticholinergic and antidopaminergic effects. The substance is medically used for the treatment of nausea, allergies, and as a sedative. Due to its sedative effects and anticholinergic side effects, caution is advised.
Mechanism of Action
- H1 antagonist
- M1 antagonist
Names / Identifiers
IUPAC: Promethazine
Mechanism of Action
Promethazin wirkt hauptsächlich als Antagonist am H1-Histaminrezeptor und hat auch anticholinerge Eigenschaften.
Effects
Effects described from scientific sources. Individual experiences vary.
Dosage
Individual sensitivity varies. Not a dosage recommendation.
Duration
Risks & Warnings
Warnings
- Glaucoma
- Prostatic hyperplasia
- Pregnancy
Known Risks
- medium
- Mögliche Nebenwirkungen umfassen Schläfrigkeit, Schwindel und anticholinerge Effekte.
Safer Use
- Start at a low dose.
- Do not combine with alcohol or other sedatives.
- Be aware of possible allergic reactions.
Harm reduction tips do not replace medical advice.
Known Interactions
- Alcohol
- Benzodiazepines
- Opioids
This list is not exhaustive. Interactions can have unpredictable effects.
Legal Status
Not legal advice. Status may change.
Entdecken
Ähnliche Substanzen
Basierend auf Substanzklasse, Rezeptoren, Wirkmechanismen und Wirkprofil.
Gemeinsame Wirkungsmuster
Wirkungen, die Promethazine mit verwandten Substanzen teilt.