Synapedia

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Prochlorperazine

Prochlorperazine is a typical antipsychotic from the group of phenothiazines, primarily used as an antiemetic and for the treatment of psychoses. It acts primarily by blocking dopamine D2 receptors in the central nervous system, leading to a reduction in nausea and psychotic symptoms. Side effects may include extrapyramidal symptoms and sedation. The substance is mainly used in clinical practice and requires medical supervision.

Depressiva
Depressiva
Dopamin-D2-Rezeptoren
Serotonin-5-HT2-Rezeptoren

Mechanism of Action

  • 5-HT2A antagonist
  • D2 receptor antagonist

Names / Identifiers

IUPAC: Prochlorperazine

prochlorperazine
58-38-8
Prochlorperazin
Prochlorpromazine
Chlormeprazine
Chlorperazine
Procloperazine
Capazine
Proclorperazine
Meterazine

Mechanism of Action

Prochlorperazine wirkt hauptsächlich als Antagonist an Dopamin-D2-Rezeptoren im zentralen Nervensystem, was zur Reduktion von psychotischen Symptomen führt.

Effects

Antipsychotisch
Sedierend
Antiemetisch
Anxiolytisch
Antihistaminisch
Anticholinerg
Neuroleptisch

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak2-4 hours
NotesThe duration of action may vary depending on individual response.
Onset30-60 minutes
Total6-12 hours
After EffectsVariable

Risks & Warnings

Warnings

  • Hypersensitivity to prochlorperazine.
  • Severe liver disease.

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Sedierung, extrapyramidale Symptome und Gewichtszunahme.

Safer Use

  • Conduct regular medical check-ups.
  • Be aware of possible side effects.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Increased sedative effect with alcohol.
  • Interactions with other antipsychotics.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesIn vielen Ländern ist Prochlorperazine nur auf Rezept erhältlich.

Not legal advice. Status may change.