Translated automatically – community improvements welcome.
Nozinan
Methotrimeprazin (Levomepromazine) is a phenothiazine derivative with antipsychotic and sedative effects. It primarily acts by blocking dopamine-D2 and serotonin-5-HT2A receptors and additionally possesses antihistaminic and anticholinergic properties. The substance is used in psychiatry for the treatment of psychoses and for sedation; it is also applied in palliative medicine for pain and symptom control. Side effects may include sedation, orthostatic hypotension, and anticholinergic effects.
Mechanism of Action
- 5-HT2A receptor antagonist
- D2 receptor antagonist
- H1 receptor antagonist
- muscarinic receptor antagonist
Names / Identifiers
IUPAC: Methotrimeprazine (Levomepromazine)
Effects
Effects described from scientific sources. Individual experiences vary.
Dosage
Individual sensitivity varies. Not a dosage recommendation.
Duration
Risks & Warnings
Warnings
- Known hypersensitivity to phenothiazines.
- Severe liver disease.
Known Risks
- medium
- Mögliche Nebenwirkungen umfassen Sedierung, anticholinerge Effekte und extrapyramidale Symptome.
Safer Use
- Start at a low dose.
- Regular medical check-ups.
Harm reduction tips do not replace medical advice.
Known Interactions
- Increased sedative effect with alcohol.
- Interactions with other antipsychotics.
This list is not exhaustive. Interactions can have unpredictable effects.
Legal Status
Not legal advice. Status may change.