Synapedia

Translated automatically – community improvements welcome.

Sertindole

Sertindole is an atypical antipsychotic primarily used for the treatment of schizophrenia. It acts by blocking dopamine-D2 and serotonin-5-HT2A receptors and additionally shows an affinity for alpha-1-adrenergic receptors. Due to its pharmacological profile, it may cause side effects such as QT prolongation, necessitating careful monitoring.

Antipsychotika

Mechanism of Action

  • 5-HT2A antagonist
  • D2 receptor antagonist

Names / Identifiers

IUPAC: Sertindole

SERTINDOLE
106516-24-9
SerLect
Serdolect
Sertindol
Sertindolum
Lu 23-174
zerdol
Lu-23-174
GVV4Z879SP

Mechanism of Action

Sertindole wirkt als Antagonist an den Serotonin-5-HT2A- und Dopamin-D2-Rezeptoren, was zu einer Modulation der Neurotransmitteraktivität im Gehirn führt.

Effects

Sedierung
Antipsychotische Wirkung
Angstlinderung
Stimmungsverbesserung
Kognitive Beeinflussung

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 hours
NotesEffects may vary depending on individual metabolism.
Onset1-3 hours
Total24 hours
After Effects12-24 hours

Risks & Warnings

Warnings

  • Do not use in case of known hypersensitivity to sertindole.
  • Use with caution in patients with cardiovascular diseases.

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Sedierung, Gewichtszunahme und extrapyramidale Symptome.

Safer Use

  • Conduct regular medical check-ups.
  • Monitor for side effects and seek medical advice if necessary.

Harm reduction tips do not replace medical advice.

Known Interactions

  • May interact with other centrally acting substances.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesSertindole ist in vielen Ländern als antipsychotisches Medikament zugelassen.

Not legal advice. Status may change.

Entdecken

Ähnliche Substanzen

Basierend auf Substanzklasse, Rezeptoren, Wirkmechanismen und Wirkprofil.

Gemeinsame Wirkungsmuster

Wirkungen, die Sertindole mit verwandten Substanzen teilt.

angstlinderung
auch beiKratom
sedierung
auch beiKratom