Synapedia

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Nortriptyline

Nortriptyline is a tricyclic antidepressant that primarily acts by inhibiting the reuptake of norepinephrine and serotonin. It also possesses anticholinergic and antihistaminergic properties, which can lead to sedating effects. The substance is mainly used for the treatment of depression and can cause side effects such as dry mouth and drowsiness. Due to its pharmacological profile, careful medical monitoring is required.

Antidepressiva

Mechanism of Action

  • Norepinephrine reuptake inhibitor
  • Serotonin reuptake inhibitor

Names / Identifiers

IUPAC: Nortriptyline

nortriptyline
72-69-5
Noramitriptyline
Desitriptilina
Ateben
Avantyl
Lumbeck
Desmethylamitriptyline
Noritren
Sensaval

Effects

Antidepressiv
Sedierend
Anxiolytisch
Analgetisch
Anticholinerg

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 weeks
NotesEffects may vary from person to person.
Onset1-3 weeks
Total24 hours
After EffectsMay last up to several days

Risks & Warnings

Warnings

  • Acute myocardial infarction
  • Pregnancy
  • Breastfeeding

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Sedierung, Mundtrockenheit und Gewichtszunahme.

Safer Use

  • Start at a low dose.
  • Regular medical check-ups.
  • Be aware of interactions with other medications.

Harm reduction tips do not replace medical advice.

Known Interactions

  • MAO inhibitors
  • Alcohol
  • Benzodiazepines

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesNortriptyline ist in vielen Ländern als verschreibungspflichtiges Medikament eingestuft.

Not legal advice. Status may change.