Synapedia

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Reserpine

Reserpine is a plant alkaloid that acts as an antihypertensive by inhibiting the storage of monoamines in synaptic vesicles. This leads to a depletion of neurotransmitters such as dopamine, norepinephrine, and serotonin. Due to its mechanism of action, reserpine can induce sedative effects and is used in the treatment of hypertension. Side effects may include depressive symptoms.

Antidepressiva
Depressiva
Antidepressiva
Monoamintransporter
Dopaminrezeptoren
Serotoninrezeptoren

Mechanism of Action

Names / Identifiers

IUPAC: Reserpine

reserpine
50-55-5
Serpalan
Serpasil
Apoplon
Sandril
Serpivite
Alserin
Rau-Sed
(-)-Reserpine

Mechanism of Action

Reserpin wirkt, indem es die Speicherung von Monoaminen in den synaptischen Vesikeln hemmt, was zu einer Verringerung der Verfügbarkeit von Neurotransmittern wie Dopamin, Noradrenalin und Serotonin führt.

Effects

Sedierung
Antidepressiv
Antihypertensiv
Angstlindernd
Neurotransmittermodulation

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 hours
NotesEffect may vary depending on individual sensitivity.
Onset1-2 hours
Total24 hours
After EffectsUp to 48 hours

Risks & Warnings

Warnings

  • Pregnancy
  • Breastfeeding
  • Certain cardiovascular diseases

Known Risks

  • medium
  • Kann zu Sedierung, Hypotonie und Depression führen.

Safer Use

  • Start at a low dose.
  • Regular medical monitoring.
  • Avoid alcohol and other sedatives.

Harm reduction tips do not replace medical advice.

Known Interactions

  • MAO inhibitors
  • Antidepressants
  • Antihypertensives

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesWird hauptsächlich zur Behandlung von Bluthochdruck und bestimmten psychischen Erkrankungen eingesetzt.

Not legal advice. Status may change.

Entdecken

Ähnliche Substanzen

Basierend auf Substanzklasse, Rezeptoren, Wirkmechanismen und Wirkprofil.

Gemeinsame Wirkungsmuster

Wirkungen, die Reserpine mit verwandten Substanzen teilt.

sedierung
auch beiKratom