Translated automatically – community improvements welcome.

Nefazodone

Nefazodone is an antidepressant from the SARI class that acts by inhibiting serotonin reuptake and has antagonistic effects at 5-HT2A and 5-HT2C receptors. It is used to treat depression and additionally possesses anxiolytic and sedative properties. Due to potential side effects, particularly liver damage, careful medical monitoring is required.

Antidepressivum

Mechanism of Action

5-HT2A antagonist
5-HT2C antagonist
SERT inhibitor

Detailed mechanism of action

Names / Identifiers

IUPAC: Nefazodone

nefazodone

83366-66-9

Nefazodona

Nefazodonum

Nefazodonum [Latin]

59H4FCV1TF

CHEBI:7494

DTXSID2023357

Nefazodonum (Latin)

RefChem:57773

Effects

Antidepressiv

Anxiolytisch

Sedierend

Stimmungsaufhellend

Appetitanregend

Schlaffördernd

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 weeks

NotesEffects may build up over several weeks.

Onset1-2 weeks

TotalLong-term use

After EffectsVariable

Risks & Warnings

Warnings

Severe liver disease
Allergies to nefazodone

Known Risks

medium
Mögliche Nebenwirkungen umfassen Schläfrigkeit, Schwindel und gastrointestinale Beschwerden.

Safer Use

Start at a low dose.
Regular medical check-ups.
Be aware of interactions with other medications.

Harm reduction tips do not replace medical advice.

Known Interactions

MAO inhibitors
other serotonin reuptake inhibitors

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig

CHVerschreibungspflichtig

DEVerschreibungspflichtig

USVerschreibungspflichtig

NotesIn vielen Ländern ist Nefazodon aufgrund von Sicherheitsbedenken reguliert.

Not legal advice. Status may change.