Translated automatically – community improvements welcome.

Mirtazapine

Mirtazapine is a noradrenergic and specifically serotonergic antidepressant that primarily acts through antagonism at α2-adrenergic receptors and various serotonin receptors. It is commonly used for the treatment of depression and sleep disorders and is characterized by sedative effects. The substance affects multiple neurotransmitter systems, leading to a complex effect profile. Side effects may include drowsiness and weight gain.

Antidepressivum

Mechanism of Action

5-HT2A Antagonist
5-HT3 Antagonist
α2-Adrenozeptor-Antagonist

Detailed mechanism of action

Names / Identifiers

IUPAC: Mirtazapine

mirtazapine

85650-52-8

Remeron

Mepirzepine

6-Azamianserin

Remergon

Zispin

Promyrtil

Remergil

Rexer

Effects

Antidepressiv

Sedierend

Angstlösend

Appetitanregend

Schlaf fördernd

Neurotransmittermodulation

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 hours

NotesEffects may vary from person to person.

Onset1-2 hours

Total24 hours

After EffectsVariable, often fatigue

Risks & Warnings

Warnings

Allergy to Mirtazapine.
Pregnancy and breastfeeding without medical supervision.

Known Risks

medium
Mögliche Nebenwirkungen umfassen Sedierung, Gewichtszunahme und Veränderungen im Blutbild.

Safer Use

Start at a low dose.
Regular medical check-ups.

Harm reduction tips do not replace medical advice.

Known Interactions

Alcohol may enhance the sedative effect.
Caution with concurrent use of other antidepressants.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig

CHVerschreibungspflichtig

DEVerschreibungspflichtig

USVerschreibungspflichtig

NotesMirtazapin ist in vielen Ländern als verschreibungspflichtiges Medikament eingestuft.

Not legal advice. Status may change.