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Metergoline

Metergoline is an ergot alkaloid with dopaminergic and serotonergic effects, primarily used as a prolactin inhibitor. It acts as a dopamine D2 agonist and blocks certain serotonin receptors, leading to a complex pharmacological effect. Due to its vasoconstrictive properties, it should be used with caution. The substance is medically used for the treatment of hormonal disorders.

Ergotalkaloid

Mechanism of Action

  • 5-HT2A antagonist
  • Dopamin-D2 agonist

Names / Identifiers

IUPAC: Metergoline

metergoline
17692-51-2
Liserdol
Metergolin
Methergoline
Metergolina
Metergolinum
FI 6337
FI-6337
(+)-N-(Carboxy)-1-methyl-9,10-dihydrolysergamine benzyl ester

Effects

Prolaktinhemmung
Vasokonstriktion
Sedierung
Antiemetische Wirkung
Erhöhung der Herzfrequenz

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak3-4 hours
NotesDuration of action may vary depending on individual sensitivity.
Onset1-2 hours
Total8-12 hours
After Effects2-4 hours

Risks & Warnings

Warnings

  • Do not use in the presence of existing cardiovascular diseases.
  • Caution during pregnancy and breastfeeding.

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Übelkeit, Schwindel und vasokonstriktive Effekte.

Safer Use

  • Start at a low dose.
  • Be aware of possible interactions with other medications.

Harm reduction tips do not replace medical advice.

Known Interactions

  • May interact with other serotonergic substances.
  • Caution when taken simultaneously with dopamine agonists.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATNicht klassifiziert, jedoch reguliert
CHNicht klassifiziert, jedoch reguliert
DENicht klassifiziert, jedoch reguliert
USNicht klassifiziert, jedoch reguliert
NotesDie rechtliche Einstufung kann je nach Verwendung variieren.

Not legal advice. Status may change.

Entdecken

Ähnliche Substanzen

Basierend auf Substanzklasse, Rezeptoren, Wirkmechanismen und Wirkprofil.

Gemeinsame Wirkungsmuster

Wirkungen, die Metergoline mit verwandten Substanzen teilt.

sedierung
auch beiKratom