Synapedia

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Thioridazine

Thioridazine is a typical antipsychotic from the group of phenothiazines, primarily acting through dopamine D2 receptor antagonism. It is used for the treatment of schizophrenia and other psychotic disorders. Side effects may include cardiac and neurological risks, necessitating careful monitoring.

Antipsychotika
Antidepressiva
Dopaminrezeptoren
Serotoninrezeptoren

Mechanism of Action

  • 5-HT2A antagonist
  • D2 receptor antagonist

Names / Identifiers

IUPAC: Thioridazine

thioridazine
50-52-2
Mellaril
Thioridazin
Mellerette
Sonapax
Malloryl
Meleril
Melleril
Mellaril-S

Mechanism of Action

Thioridazin wirkt hauptsächlich als Antagonist an Dopaminrezeptoren, insbesondere D2-Rezeptoren, was zu einer Reduktion von psychotischen Symptomen führt.

Effects

Antipsychotisch
Sedierend
Anxiolytisch
Antiemetisch
Neuroleptisch

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 hours
NotesEffect may vary depending on individual response.
Onset1-2 hours
Total24 hours
After EffectsUp to 24 hours

Risks & Warnings

Warnings

  • Do not use in known hypersensitivity to thioridazine.
  • Caution in patients with liver or heart problems.

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Sedierung, Gewichtszunahme und extrapyramidale Symptome.

Safer Use

  • Conduct regular medical check-ups.
  • Monitor for side effects and report them.

Harm reduction tips do not replace medical advice.

Known Interactions

  • May interact with other centrally acting substances.
  • Avoidance of alcohol is recommended.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesThioridazin ist in vielen Ländern aufgrund seiner Nebenwirkungen und des Risikos von Herzrhythmusstörungen reguliert.

Not legal advice. Status may change.