DMT
smokedDOSE:
35 mg
smoked
DMT
DMT
Laden…
2-(1H-indol-3-yl)ethyl-dimethyl-amine
DMT (Dimethyltryptamine) is a naturally occurring psychedelic tryptamine, characterized primarily by its strong and short-lasting hallucinogenic effects. It acts primarily as an agonist at serotonin receptors, particularly 5-HT2A, and induces intense visual and sensory alterations. Due to its short duration of action and potential psychological burden, a moderate risk profile is assumed. DMT is found in various plants and in the human body and is being studied in research on consciousness.
Class
Psychedelika
Pharmacological context
Mechanism
DMT primarily acts as an agonist at the 5-HT2A receptor, leading to the...
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
Moderate Risk
Condensed from structured notes
Receptor Targets
Mechanism of Action
Designations
IUPAC: 2-(1H-indol-3-yl)ethyl-dimethyl-amine
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Synapedia Evidence
DMT primarily acts as an agonist at the 5-HT2A receptor, leading to the characteristic psychedelic effects. It also affects other serotonin receptors, which increases the complexity of its effects.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Reported range 40–60 mg
Total duration 30–60 minutes (smoked/vaporized), 2–4 hours (oral)
Oral
| Tier | Dosage |
|---|---|
| Light | 20–40 mg |
| Reported | 40–60 mg |
| Strong | 60–100 mg |
Geraucht
| Tier | Dosage |
|---|---|
| Light | 20–30 mg |
| Reported | 30–50 mg |
| Strong | 50–70 mg |
Vaporisiert
| Tier | Dosage |
|---|---|
| Light | 20–30 mg |
| Reported | 30–50 mg |
| Strong | 50–70 mg |
Onset
2–5 minutes (smoked/vaporized), 15–30 minutes (oral)
Peak
20–30 minutes (smoked/vaporized), 1–2 hours (oral)
Total duration
30–60 minutes (smoked/vaporized), 2–4 hours (oral)
After effects
1–2 hours
Avoid uncertain dosage claims and do not infer numbers when data is unclear.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Community summaries. Not consumption guidance.
DMT
Experiences + discussions about DMT
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Based on substance class, receptors, mechanisms, and effect profile.
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