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2C-B

2C-B is a synthetic psychedelic from the phenethylamine class, primarily characterized by its action as a 5-HT2A agonist. It induces altered perceptions, visual effects, and emotional enhancement. The substance is often used in psychonautical research but has a moderate risk profile, especially with improper use.

Psychedelika
Phenethylamine
Moderate risk
5-HT2A
5-HT2C

Mechanism of Action

  • 5-HT2A agonist
Detailed mechanism of action

Names / Identifiers

IUPAC: 2-(4-bromo-2,5-dimethoxy-phenyl)ethylamine

4-Bromo-2,5-dimethoxyphenethylamine
66142-81-2
2-(4-Bromo-2,5-dimethoxyphenyl)ethylamine
2,5-Dimethoxy-4-bromophenethylamine
2-(4-Bromo-2,5-dimethoxyphenyl)ethanamine
4-Bromo-2,5-dimethoxyphenylethylamine
Benzeneethanamine, 4-bromo-2,5-dimethoxy-
V77772N32H
CHEBI:189669
RefChem:82888

Mechanism of Action

2C-B primarily acts as an agonist at the 5-HT2A receptor, leading to altered perceptions and emotional effects. The activation of additional serotonin receptors may also contribute to its effects.

Effects

increased empathy
improved mood
creative thought processes
altered perception of time
nausea
anxiety
confusion

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start with a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak2-4 hours
NotesDuration may vary depending on dose and individual sensitivity.
Onset30-90 minutes
Total4-8 hours
After Effects1-3 hours

Risks & Warnings

Warnings

  • Not suitable for individuals with mental disorders.

Known Risks

  • medium
  • Mögliche psychische Effekte, insbesondere bei hohen Dosen.

Safer Use

  • Consume in a safe environment.
  • Do not consume alone.
  • Pay attention to one's mental health.

Harm reduction tips do not replace medical advice.

Known Interactions

  • May interact with other serotonergic substances.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATNicht legal (Suchtmittelgesetz)
CHNicht legal (Betäubungsmittelgesetz)
DENicht legal (Betäubungsmittelgesetz)
USNicht legal (Controlled Substances Act)
Notes2C-B fällt in vielen Ländern unter die Regelungen für psychoaktive Substanzen.

Not legal advice. Status may change.

Receptor Targets(2 in KG)

5-HT2A

Der 5-HT2A-Rezeptor ist ein Serotonin-Rezeptor der Klasse Gq-gekoppelter GPCRs. Er ist der primäre molekulare Angriffspunkt klassischer Psychedelika und spielt eine Rolle bei Kognition und Wahrnehmung.

metabotropic
80%

5-HT2C

Der 5-HT2C-Rezeptor ist ein Gq/11-gekoppelter Serotoninrezeptor, der an der Regulation von Appetit, Stimmung und Angst beteiligt ist. Er wird von verschiedenen Psychedelika als sekundäres Ziel aktiviert und moduliert dopaminerge Signalwege.

metabotropic
80%

Known Interactions

Starke serotonerge Synergie und kardiovaskuläre Belastung

MDMA
High
Show all interactions

Entdecken

Gemeinsame Wirkungsmuster

Wirkungen, die 2C-B mit verwandten Substanzen teilt.

angst
auch beiAmphetamin, Methamphetamin, Kokain
übelkeit
auch beiPsilocybin, Ketamin
verwirrtheit
auch beiKetamin