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1-(3-cyano-3,3-diphenylpropyl)-4-piperidin-1-ylpiperidine-4-carboxamide
Piritramid is a synthetic opioid primarily used for the treatment of severe pain. It acts primarily as a μ-opioid receptor agonist and has a high potential for dependence as well as risks such as respiratory depression. Due to its efficacy and side effects, careful medical use is necessary.
Receptor Targets
Mechanism of Action
Designations
IUPAC: 1-(3-cyano-3,3-diphenyl-propyl)-4-piperidino-isonipecotamide
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Receptor Profile
Der Serotonintransporter (SERT/5-HTT) ist ein Natrium-abhängiger Monoamintransporter, der Serotonin aus dem synaptischen Spalt zurück in die präsynaptische Zelle transportiert. Er ist das primäre Ziel von SSRI und MDMA.
Der Noradrenalintransporter (NET) ist ein Monoamintransporter, der Noradrenalin aus dem synaptischen Spalt zurücktransportiert. Er wird von verschiedenen Stimulants und Antidepressiva beeinflusst.
Substance Fingerprint
Pharmacological profile based on receptor binding, mechanism of action, and substance class. Limited data — interpret profile with caution.
Synapedia Evidence
Effects & Pharmacology is partially translated. Some details are still being expanded.
Piritramid wirkt hauptsächlich als Agonist an μ-Opioid-Rezeptoren im zentralen Nervensystem, was zu einer Schmerzlinderung führt.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Total duration 4-6 hours
Peak
1-2 hours
Onset
30-60 minutes
Total duration
4-6 hours
After effects
2-4 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Risiko von Abhängigkeit und Atemdepression.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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