Synapedia

Translated automatically – community improvements welcome.

Tapentadol

Tapentadol is an opioid analgesic with a dual mechanism of action as a μ-opioid receptor agonist and norepinephrine reuptake inhibitor. It is used for the treatment of moderate to severe pain and is characterized by lower nausea and sedation compared to classical opioids. The potential for dependence is present, but moderate compared to other opioids. The combination of mechanisms may enhance analgesic efficacy.

Analgetika

Mechanism of Action

  • Norepinephrine reuptake inhibitor
  • μ-opioid receptor agonist

Names / Identifiers

IUPAC: Tapentadol

Tapentadol
175591-23-8
CG5503
BN 200 (BASE)
CG5503 (BASE)
BN 200
BN-200
CG-5503
CG5503 IR
3-((1R,2R)-3-(Dimethylamino)-1-ethyl-2-methylpropyl)phenol

Effects

Schmerzlinderung
Entspannung
Sedierung
Euphorie
Angstlinderung
Müdigkeit
Appetitanregung

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteConsider individual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak1-2 hours
NotesEffect may vary depending on individual metabolism.
Onset30-60 minutes
Total4-6 hours
After Effects2-4 hours

Risks & Warnings

Warnings

  • Severe respiratory depression.
  • Acute or severe asthma attacks.

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Übelkeit, Schwindel und Sedierung. Risiko einer Abhängigkeit.

Safer Use

  • Start at a low dose.
  • Avoid polydrug use with other sedating substances.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Enhancement of effects of other opioids.
  • Interactions with MAO inhibitors.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesIn vielen Ländern ist Tapentadol aufgrund seines Missbrauchspotenzials reguliert.

Not legal advice. Status may change.

Entdecken

Gemeinsame Wirkungsmuster

Wirkungen, die Tapentadol mit verwandten Substanzen teilt.

euphorie
auch beiKratom, MDMA, Amphetamin+3 weitere
schmerzlinderung
auch beiKratom, SSRI, Ketamin
entspannung
auch beiKratom, MDMA
angstlinderung
auch beiKratom
sedierung
auch beiKratom