Laden…
methyl (2S,4aR,6aR,7R,9S,10aS,10bR)-9-acetyloxy-2-(furan-3-yl)-6a,10b-dimethyl-4,10-dioxo-2,4a,5,6,7,8,9,10a-octahydro-1H-benzo[f]isochromene-7-carboxylate
Salvinorin A is a potent, naturally occurring psychedelic that primarily acts as a Kappa-opioid receptor agonist. It differs from classical psychedelics due to its unique mechanism of action without direct effects on serotonin receptors. The substance is derived from the plant Salvia divinorum and can induce intense, short-lasting alterations in consciousness. Due to its strong effects and potential psychological burden, a moderate risk profile is assumed.
Class
Dissoziativa
Pharmacological context
Mechanism
Salvinorin A primarily acts as an agonist at the Kappa-opioid receptor,...
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
Interpret risks carefully
Condensed from structured notes
Receptor Targets
Mechanism of Action
Designations
IUPAC: Salvinorin A
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Synapedia Evidence
Salvinorin A primarily acts as an agonist at the Kappa-opioid receptor, leading to its psychedelic effects. It influences perception and consciousness by modulating neuronal activity in specific brain regions.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Reported range 2–5 mg
Total duration 30–60 minutes
Sublingual
| Tier | Dosage |
|---|---|
| Light | 1–2 mg |
| Reported | 2–5 mg |
| Strong | 5–10 mg |
Geraucht
| Tier | Dosage |
|---|---|
| Light | 0.5–1 mg |
| Reported | 1–2 mg |
| Strong | 2–5 mg |
Peak
5–15 minutes
Total duration
30–60 minutes
After effects
1–2 hours
Avoid uncertain dosage claims and do not infer numbers when data is unclear.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Evidence
limited
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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