Synapedia

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Pimozide

Pimozide is a typical antipsychotic from the class of diphenylbutylpiperidines, primarily acting as a dopamine D2 receptor antagonist. It is mainly used for the treatment of chronic psychotic disorders and tic disorders. Due to its pharmacological profile, it can cause extrapyramidal side effects and cardiac risks, which necessitates careful monitoring.

Antipsychotika
Antidepressiva
Dopamin-D2-Rezeptor
Serotonin-5-HT2-Rezeptor

Mechanism of Action

  • Dopamin-D2-Antagonist

Names / Identifiers

IUPAC: Pimozide

pimozide
2062-78-4
Orap
Opiran
Pimozidum
McN-JR-6238
pimozida
Neoperidole
R-6238
R 6238

Mechanism of Action

Pimozid wirkt hauptsächlich als Antagonist an Dopamin-D2-Rezeptoren, was zu einer Reduktion der dopaminergen Aktivität im zentralen Nervensystem führt.

Effects

Antipsychotisch
Sedierend
Anxiolytisch
Antiemetisch
Neuroleptisch

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 hours
NotesEffect may vary depending on individual response.
Onset1-3 hours
Total24 hours
After EffectsUp to 24 hours

Risks & Warnings

Warnings

  • Known hypersensitivity to pimozide
  • Severe cardiac arrhythmias

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Sedierung, Gewichtszunahme und extrapyramidale Symptome.

Safer Use

  • Regular medical monitoring
  • Slow dose adjustment
  • Watch for signs of side effects

Harm reduction tips do not replace medical advice.

Known Interactions

  • Increased sedative effect with alcohol
  • Interactions with other antipsychotics

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesIn vielen Ländern ist Pimozid nur auf Rezept erhältlich.

Not legal advice. Status may change.