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Perazine

Perazine is a typical antipsychotic from the group of phenothiazines, primarily acting through dopamine-D2 and serotonin-5-HT2A receptor antagonism. It is used for the treatment of schizophrenia and other psychotic disorders. Side effects may include sedation, extrapyramidal symptoms, and cardiovascular effects. The substance has a moderate risk profile, especially with long-term use.

Antipsychotika
Antidepressiva
Dopamin-D2-Rezeptor
Serotonin-5-HT2A-Rezeptor

Mechanism of Action

  • Dopamin-D2 antagonist
  • Serotonin-5-HT2A antagonist
Detailed mechanism of action

Names / Identifiers

IUPAC: Perazine

PERAZINE
Pernazine
84-97-9
N-(3-(4-Methyl-1-piperazinyl)propyl)phenothiazine
10-(3-(4-Methylpiperazin-1-yl)propyl)-10H-phenothiazine
N-Methyl-piperazinyl-N'-propyl-phenothiazin
DTXSID6048628
10-[3-(4-methylpiperazin-1-yl)propyl]-10H-phenothiazine
8915147A2B
DTXCID3028554

Mechanism of Action

Perazine wirkt als Antagonist an Dopamin-D2- und Serotonin-5-HT2A-Rezeptoren, was zur Reduktion von psychotischen Symptomen führt.

Effects

Antipsychotisch
Sedierend
Extrapyramidale Symptome
Kardiovaskuläre Effekte
Angstlindernd
Stimmungsstabilisierend

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 hours
NotesDuration of action may vary depending on individual metabolism.
Onset1-2 hours
Total24 hours
After EffectsVariable

Risks & Warnings

Warnings

  • Do not use in case of known hypersensitivity to phenothiazines.

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Sedierung und extrapyramidale Symptome.

Safer Use

  • Start at a low dose.
  • Regular medical check-ups should be taken.

Harm reduction tips do not replace medical advice.

Known Interactions

  • May interact with other centrally acting substances.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesIn vielen Ländern ist Perazin nur auf Rezept erhältlich.

Not legal advice. Status may change.