Synapedia

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Paroxetine

Paroxetine is a selective serotonin reuptake inhibitor primarily used for the treatment of depression and anxiety disorders. It increases serotonin concentration in the synaptic cleft by inhibiting the serotonin transporter. The substance can cause side effects and should be used under medical supervision. Abrupt discontinuation can lead to withdrawal symptoms.

Antidepressiva
Antidepressiva
Serotonin-Transporter

Mechanism of Action

Names / Identifiers

IUPAC: Paroxetine

paroxetine
61869-08-7
Frosinor
Motivan
Casbol
PaxPar
Paroxetina
Paroxetinum
Aropax
(-)-Paroxetine

Mechanism of Action

Paroxetin wirkt als selektiver Serotonin-Wiederaufnahmehemmer (SSRI), indem es die Wiederaufnahme von Serotonin in die präsynaptischen Neuronen hemmt, was zu einer erhöhten Verfügbarkeit von Serotonin im synaptischen Spalt führt.

Effects

Antidepressiv
Angstlösend
Stimmungsaufhellend
Anxiolytisch
Sedierend

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak4-6 weeks
NotesThe effect may build up over several weeks.
Onset1-2 weeks
Total24 hours
After Effectsunknown

Risks & Warnings

Warnings

  • Pregnancy
  • Breastfeeding
  • Liver diseases

Known Risks

  • medium
  • Nebenwirkungen können auftreten, darunter Übelkeit, Schwindel und sexuelle Dysfunktion.

Safer Use

  • Start at a low dose
  • Regular medical check-ups
  • Inform about possible side effects

Harm reduction tips do not replace medical advice.

Known Interactions

  • MAO inhibitors
  • other SSRIs
  • anticoagulants

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesParoxetin ist in vielen Ländern als Medikament zugelassen und unterliegt daher strengen Vorschriften.

Not legal advice. Status may change.