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Lorazepam

Lorazepam is a benzodiazepine that primarily acts by enhancing GABA-A receptor activity. It is medically used for the treatment of anxiety disorders, sleep disturbances, and seizures. The substance possesses sedative, anxiolytic, and muscle-relaxant properties. Due to its potential for dependence, Lorazepam should only be used under medical supervision.

Benzodiazepine

Mechanism of Action

  • GABA-A receptor agonist
Detailed mechanism of action

Names / Identifiers

IUPAC: Lorazepam

Mechanism of Action

Lorazepam wirkt als Agonist am GABA-A-Rezeptor, was zu einer verstärkten Hemmung der neuronalen Aktivität führt und anxiolytische sowie sedative Effekte hervorruft.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak2-4 hours
NotesEffect may vary depending on dose and individual sensitivity.
Onset30-60 minutes
Total6-8 hours
After Effects2-4 hours

Risks & Warnings

Warnings

  • Pregnancy
  • Breastfeeding
  • Severe respiratory diseases

Known Risks

  • medium
  • Mögliche Abhängigkeit, Sedierung, Gedächtnisstörungen.

Safer Use

  • Start at a low dose
  • Avoid alcohol and other sedatives
  • Regular medical monitoring

Harm reduction tips do not replace medical advice.

Known Interactions

  • Alcohol
  • Opioids
  • Antidepressants

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesLorazepam ist in vielen Ländern aufgrund seines Abhängigkeitspotenzials reguliert.

Not legal advice. Status may change.