Synapedia

Translated automatically – community improvements welcome.

Exalgo

Hydromorphone is a potent opioid analgesic that primarily acts as a μ-opioid receptor agonist. It is used for the treatment of severe pain and has a high potential for dependence and abuse. The substance can lead to respiratory depression and other serious side effects, which necessitates careful handling.

Opioide
Opioide
μ-Opioidrezeptor

Mechanism of Action

  • μ-opioid receptor agonist

Names / Identifiers

IUPAC: Hydromorphone

hydromorphone
Dihydromorphinone
Dimorphone
Hydromorphon
Idromorfone
Novolaudon
Dihydromorfinon
Hidromorfona
Hydromorfona
Laudacon

Mechanism of Action

Hydromorphon wirkt hauptsächlich als Agonist am μ-Opioidrezeptor, was zu einer Hemmung der Schmerzübertragung im zentralen Nervensystem führt.

Effects

Schmerzlinderung
Sedierung
Euphorie
Entspannung
Atemdepression
Übelkeit
Verstopfung
Abhängigkeit
Toleranz
Entzugserscheinungen

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak30-60 minutes
NotesDuration of action may vary depending on dose and individual response.
Onset10-30 minutes
Total4-6 hours
After Effects2-4 hours

Risks & Warnings

Warnings

  • Respiratory insufficiency
  • severe liver or kidney disease
  • pregnancy

Known Risks

  • high
  • Hohe Abhängigkeit und Missbrauchspotenzial, Atemdepression möglich.

Safer Use

  • Start at a low dose
  • Avoid polydrug use with other depressants
  • Regular medical check-ups

Harm reduction tips do not replace medical advice.

Known Interactions

  • Benzodiazepines
  • Alcohol
  • other opioids

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig (Schedule II)
NotesIn vielen Ländern ist Hydromorphone aufgrund seines Missbrauchspotenzials streng reguliert.

Not legal advice. Status may change.

Entdecken

Gemeinsame Wirkungsmuster

Wirkungen, die Exalgo mit verwandten Substanzen teilt.

euphorie
auch beiKratom, MDMA, Amphetamin+3 weitere
schmerzlinderung
auch beiKratom, Ketamin, SSRI
übelkeit
entspannung
auch beiKratom, MDMA
sedierung
auch beiKratom