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Etizolam

Etizolam is a thienodiazepine-like sedative with anxiolytic, hypnotic, and muscle-relaxant properties. It primarily acts as an agonist at the GABA-A receptor, leading to enhanced inhibitory neurotransmission in the central nervous system. Due to its pharmacological effects, it is therapeutically used for the treatment of anxiety disorders and sleep disturbances. The risk of dependence and withdrawal symptoms is moderate and should be considered with prolonged use.

Sedativa
GABA-A

Mechanism of Action

Names / Identifiers

IUPAC: Etizolam

Mechanism of Action

Etizolam acts as an agonist at the GABA-A receptor, resulting in enhanced inhibition of neuronal activity. This leads to anxiolytic, sedative, and muscle-relaxant effects.

Dosage

Safety NoteIndividual variation, start at low doses, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak1-2 hours
NotesDuration of effect may vary depending on dose and individual response.
Onset30-60 minutes
Total6-8 hours
After Effects2-4 hours

Risks & Warnings

Warnings

  • Pregnancy
  • Breastfeeding
  • Severe respiratory diseases

Known Risks

  • medium
  • Mögliche Abhängigkeit und Toleranzentwicklung bei längerem Gebrauch.

Safer Use

  • Start at low doses.
  • Do not combine with alcohol or other sedatives.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Alcohol
  • Opioids
  • Other benzodiazepines

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

Germanyunknown

Not legal advice. Status may change.

Receptor Targets

GABA-A

Der GABA-A-Rezeptor ist ein ligandengesteuerter Chloridkanal und der wichtigste inhibitorische Rezeptor im zentralen Nervensystem. Er besitzt multiple allosterische Bindungsstellen für verschiedene Substanzklassen.

ionotropic

Entdecken

Ähnliche Substanzen

Basierend auf Substanzklasse, Rezeptoren, Wirkmechanismen und Wirkprofil.