Laden…
5-(2-chlorophenyl)-7-nitro-1,3-dihydro-1,4-benzodiazepin-2-one
Clonazepam is a benzodiazepine that primarily acts by enhancing GABAergic inhibition in the central nervous system. It is mainly used for the treatment of epilepsy and panic disorders. The substance possesses anxiolytic, anticonvulsive, and muscle relaxant properties. Due to its potential for dependence, its use should be carefully monitored.
Class
Depressiva
Pharmacological context
Mechanism
Clonazepam acts as an agonist at the GABA-A receptor, leading to...
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
High Risk
Condensed from structured notes
Receptor Targets
Mechanism of Action
Designations
IUPAC: Clonazepam
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Receptor Profile
Der GABA-A-Rezeptor ist ein ligandengesteuerter Chloridkanal und der wichtigste inhibitorische Rezeptor im zentralen Nervensystem. Er besitzt multiple allosterische Bindungsstellen für verschiedene Substanzklassen.
Synapedia Evidence
Clonazepam acts as an agonist at the GABA-A receptor, leading to increased inhibition of neuronal activity. This results in anxiolytic, sedative, and muscle relaxant effects.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Reported range 0.5–1 mg
Total duration 6–12 hours
Oral
| Tier | Dosage |
|---|---|
| Light | 0.25 mg |
| Reported | 0.5–1 mg |
| Strong | 2 mg |
Oral
Onset
30–60 minutes
Peak
1–2 hours
Total duration
6–12 hours
Avoid uncertain dosage claims and do not infer numbers when data is unclear.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Mögliche Abhängigkeit und Toleranzentwicklung bei längerem Gebrauch.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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