Laden…
1-phenyl-2-pyrrolidin-1-ylpentan-1-one
1-Phenyl-2-pyrrolidin-1-ylpentan-1-one (α-PVP) is a synthetic stimulant belonging to the class of pyrrolidinyl cathinones. It primarily acts as a reuptake inhibitor of dopamine and norepinephrine, which can lead to increased psychomotor activity and euphoria. Due to its high potential for abuse and risks of cardiovascular and psychological adverse effects, α-PVP is classified as a high-risk substance.
Class
Not clearly classified yet
Pharmacological context
Mechanism
α-PVP functions mainly as a reuptake inhibitor of dopamine and...
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
Interpret risks carefully
Condensed from structured notes
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Designations
IUPAC: 1-phenyl-2-pyrrolidino-pentan-1-one
Synapedia Evidence
Effects & Pharmacology is partially translated. Some details are still being expanded.
α-PVP functions mainly as a reuptake inhibitor of dopamine and norepinephrine, enhancing their availability in the synaptic cleft.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Dosage & Duration translation in progress
English prose is being expanded. The German version currently has more detail.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks & Harm Reduction translation in progress
English prose is being expanded. Safety-critical structured data may still be shown when available.
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interactions translation in progress
English prose is being expanded. Safety-critical structured data may still be shown when available.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
Share a report, observation, or question about this substance. Entries are reviewed before publication and marked as unverified community signals.
These entries are submitted by users and are not verified. They may contain subjective experiences, observations, source leads, or corrections. They do not replace scientific data and are not consumption advice.
The signal hub collects approved risk signals, experience reports and source leads by relevance.