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[2-(3-fluorophenyl)-1-methyl-ethyl]amine
1-(3-fluorophenyl)propan-2-amine (3-FA) is a substituted amphetamine with stimulant effects mediated by the release and reuptake inhibition of monoamines. The substance primarily acts on dopamine, norepinephrine, and serotonin transporters, resulting in increased activity in the central nervous system. Due to its structural similarity to other fluorinated amphetamines, 3-FA may potentially exhibit neurotoxic effects, and the limited research necessitates caution in assessing its risk profile.
Translation in progress
This section is currently being translated. Content will be available soon.
View German version →Receptor Targets
Mechanism of Action
Designations
IUPAC: [2-(3-fluorophenyl)-1-methyl-ethyl]amine
Receptor Profile
Der 5-HT2A-Rezeptor ist ein Serotonin-Rezeptor der Klasse Gq-gekoppelter GPCRs. Er ist der primäre molekulare Angriffspunkt klassischer Psychedelika und spielt eine Rolle bei Kognition und Wahrnehmung.
Der Serotonintransporter (SERT/5-HTT) ist ein Natrium-abhängiger Monoamintransporter, der Serotonin aus dem synaptischen Spalt zurück in die präsynaptische Zelle transportiert. Er ist das primäre Ziel von SSRI und MDMA.
Der Dopamintransporter (DAT) ist ein Natrium-abhängiger Monoamintransporter, der Dopamin aus dem synaptischen Spalt entfernt. Er ist ein zentrales Ziel von Stimulanzien und spielt eine Schlüsselrolle im Belohnungssystem.
Substance Fingerprint
Pharmacological profile based on receptor binding, mechanism of action, and substance class. Limited data — interpret profile with caution.
Synapedia Evidence
Effects & Pharmacology is partially translated. Some content may appear in German.
3-FA acts primarily as a releasing agent and reuptake inhibitor for monoamines, particularly affecting dopamine, norepinephrine, and serotonin transporters.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Risks & Harm Reduction — Translation in progress
This section is being translated. Content is available in German.
View in German →The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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