Laden…
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Substance Comparison
Overall, the two substances share a strikingly similar pharmacological profile.
Despite belonging to different classes, these substances share receptor activity at NMDA and SERT, which may produce overlapping effects.
Ibogain has significantly higher psychedelic depth
| DXM | Ibogain | |
|---|---|---|
| Class | Dissoziativa | Psychedelika |
| Risk Level | moderate | high |
| Mechanisms | NMDA-Antagonist, SERT-Inhibitor, Sigma-1-Agonist | κ-Opioid-Agonist, NMDA-Antagonist, SERT-Inhibitor, σ-Rezeptor-Agonist |
| Receptors | NMDA, SERT, Sigma-1 | κ-Opioid, NMDA, SERT, σ-1 |
| Effects | — | — |
| Evidence | unknown | — |
No harm reduction data available
Evidence: unknown · Sources: 3
Evidence: not assessed · Sources: 2