Synapedia

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Trihexyphenidyl

Trihexyphenidyl is a centrally acting anticholinergic agent primarily used for the treatment of Parkinson's symptoms. It blocks muscarinic acetylcholine receptors and thereby exerts spasmolytic and antiparkinsonian effects. Side effects may include anticholinergic effects such as dry mouth, cognitive impairments, and tachycardia. Due to its pharmacological profile, improper use may lead to cognitive disturbances and delirium.

Anticholinergika
Antidepressiva
Muskarinische Acetylcholinrezeptoren

Mechanism of Action

  • Muscarinic antagonist

Names / Identifiers

IUPAC: Trihexyphenidyl

trihexyphenidyl
Benzhexol
144-11-6
Triphenidyl
Trihexyphenidyle
Benzhexolum
Trihexifenidilo
Trihexyphenidylum
Apo-Trihex
1-cyclohexyl-1-phenyl-3-(piperidin-1-yl)propan-1-ol

Mechanism of Action

Trihexyphenidyl wirkt als Antagonist an muskarinischen Acetylcholinrezeptoren, was zu einer Reduktion der cholinergen Aktivität im zentralen Nervensystem führt.

Effects

Anticholinerge Effekte
Sedierung
Kognitive Beeinträchtigung
Erhöhung der Herzfrequenz
Mundtrockenheit
Sehstörungen
Verstopfung

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak2-4 hours
NotesDuration of action may vary depending on dose and individual metabolism.
Onset1-2 hours
Total6-12 hours
After EffectsUnclear

Risks & Warnings

Warnings

  • Glaucoma
  • Prostate hyperplasia
  • Myasthenia gravis

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Mundtrockenheit, Schwindel und Verwirrtheit.

Safer Use

  • Start at a low dose.
  • Consider regular medical monitoring.

Harm reduction tips do not replace medical advice.

Known Interactions

  • May interact with other anticholinergics.
  • Caution with concurrent alcohol consumption.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesIn vielen Ländern ist Trihexyphenidyl nur auf Rezept erhältlich.

Not legal advice. Status may change.

Entdecken

Ähnliche Substanzen

Basierend auf Substanzklasse, Rezeptoren, Wirkmechanismen und Wirkprofil.

Gemeinsame Wirkungsmuster

Wirkungen, die Trihexyphenidyl mit verwandten Substanzen teilt.

mundtrockenheit
auch beiSSRI
sedierung
auch beiKratom