Translated automatically – community improvements welcome.
Sumatriptan
Sumatriptan is a selective agonist at 5-HT1B/1D receptors, used for the treatment of acute migraine attacks. It causes constriction of dilated blood vessels in the brain and inhibits the release of pro-inflammatory neurotransmitters. The substance is well-studied but may pose risks in certain pre-existing conditions. Sumatriptan is used exclusively for symptomatic treatment and not for prevention.
Mechanism of Action
- 5-HT1B agonist
- 5-HT1D agonist
Names / Identifiers
IUPAC: Sumatriptan
Mechanism of Action
Sumatriptan wirkt als Agonist an den Serotoninrezeptoren 5-HT_1B und 5-HT_1D, was zu einer Vasokonstriktion der intrakraniellen Blutgefäße führt und die Freisetzung von proinflammatorischen Neuropeptiden hemmt.
Effects
Effects described from scientific sources. Individual experiences vary.
Dosage
Individual sensitivity varies. Not a dosage recommendation.
Duration
Risks & Warnings
Warnings
- Pregnancy
- Cardiovascular diseases
Known Risks
- medium
- Mögliche Nebenwirkungen sind Übelkeit, Schwindel und Druckgefühl im Brustbereich.
Safer Use
- Start at a low dose
- Be aware of interactions with other medications
Harm reduction tips do not replace medical advice.
Known Interactions
- MAO inhibitors
- Serotonin reuptake inhibitors
This list is not exhaustive. Interactions can have unpredictable effects.
Legal Status
Not legal advice. Status may change.
Entdecken
Ähnliche Substanzen
Basierend auf Substanzklasse, Rezeptoren, Wirkmechanismen und Wirkprofil.