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(2S)-2-[[4-[(3-fluorophenyl)methoxy]phenyl]methylamino]propanamide
Safinamide is a selective, reversible MAO-B inhibitor used for the treatment of Parkinson's disease. It modulates dopaminergic signaling pathways and additionally affects voltage-gated sodium channels, suggesting neuroprotective effects. The substance is primarily used to improve motor symptoms and has a moderate risk profile when used correctly.
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Designations
IUPAC: (2S)-2-[[4-(3-fluorobenzyl)oxybenzyl]amino]propionamide
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Receptor Profile
Monoaminoxidase B (MAO-B) ist ein mitochondriales Enzym, das bevorzugt Phenylethylamin, Benzylamin und Dopamin abbaut. Selektive MAO-B-Hemmer werden bei Morbus Parkinson eingesetzt.
Synapedia Evidence
Effects & Pharmacology translation in progress
English prose is being expanded. The German version currently has more detail.
Total duration Long-term treatment
Peak
4-6 weeks
Onset
1-2 weeks
Total duration
Long-term treatment
After effects
Variable
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Summary
Mögliche Nebenwirkungen umfassen Übelkeit, Schwindel und Schlafstörungen.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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