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Modafinil

Modafinil is a wakefulness-promoting stimulant primarily used for the treatment of narcolepsy and other sleep disorders. It primarily acts by inhibiting the reuptake of dopamine and norepinephrine as well as by modulating the orexin system. The substance has a lower potential for abuse than classic stimulants but can cause side effects with improper use. Modafinil is also used off-label to enhance cognitive performance.

Stimulanzien
Stimulanzien
Nootropika
Dopamintransporter
Noradrenalintransporter
Orexinrezeptoren

Mechanism of Action

  • Dopamin-Wiederaufnahmehemmer
  • Noradrenalin-Wiederaufnahmehemmer
  • Orexin-Modulation

Names / Identifiers

IUPAC: Modafinil

modafinil
68693-11-8
Provigil
Modiodal
2-(Benzhydrylsulfinyl)acetamide
2-[(diphenylmethyl)sulfinyl]acetamide
2-benzhydrylsulfinylacetamide
modaphonil
CRL 40476
Modafinilo

Mechanism of Action

Modafinil wirkt durch die Hemmung der Wiederaufnahme von Dopamin und Noradrenalin sowie durch die Modulation des Orexin-Systems, was zu einer erhöhten Wachsamkeit führt.

Effects

Wachsamkeit
Konzentration
Energie
Verbesserte kognitive Funktion
Verminderte Müdigkeit

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start at a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak2-4 hours
NotesEffects may vary depending on individual sensitivity.
Onset30-60 minutes
Total10-12 hours
After Effects2-4 hours

Risks & Warnings

Warnings

  • Cardiovascular diseases.
  • Sleep disorders.
  • Pregnancy and breastfeeding.

Known Risks

  • medium
  • Mögliche Nebenwirkungen umfassen Schlaflosigkeit, Kopfschmerzen und Angstzustände.

Safer Use

  • Start at a low dose.
  • Take regular breaks.
  • Be aware of possible interactions with other medications.

Harm reduction tips do not replace medical advice.

Known Interactions

  • May interact with other stimulants.
  • Interactions with antidepressants possible.

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesModafinil ist in vielen Ländern als Medikament zur Behandlung von Schlafstörungen zugelassen.

Not legal advice. Status may change.