Laden…
2-(methylamino)-1-(4-methylphenyl)propan-1-one
Mephedrone is a synthetic stimulant from the class of cathinones, primarily acting through the inhibition of the reuptake of dopamine, norepinephrine, and serotonin. It produces stimulating and euphoric effects but can also cause side effects such as palpitations, anxiety, and neurotoxic effects. The substance is often consumed as a designer drug and carries a moderate risk for acute and chronic health damage.
Receptor Targets
Mechanism of Action
Designations
IUPAC: 2-(methylamino)-1-(p-tolyl)propan-1-one
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Synapedia Evidence
Mephedrone primarily acts as an inhibitor of the reuptake of dopamine, serotonin, and norepinephrine. This leads to an increased availability of these neurotransmitters in the synaptic cleft and enhances their effect in the central nervous system.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Total duration 3-6 hours
Peak
1-2 hours
Onset
15-30 minutes
Total duration
3-6 hours
After effects
1-3 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Neurotoxicity
possible
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
Share a report, observation, or question about this substance. Entries are reviewed before publication and marked as unverified community signals.
These entries are submitted by users and are not verified. They may contain subjective experiences, observations, source leads, or corrections. They do not replace scientific data and are not consumption advice.
The signal hub collects approved risk signals, experience reports and source leads by relevance.