Translated automatically – community improvements welcome.
Lofexidine
Lofexidine is a selective alpha-2 adrenergic receptor agonist primarily used for alleviating withdrawal symptoms in opioid dependence. It acts by inhibiting norepinephrine release, thereby reducing sympathetic overactivity. The substance has sedative and antihypertensive properties and is medically used to assist in withdrawal.
Mechanism of Action
- Alpha-2 adrenergic agonist
Names / Identifiers
IUPAC: Lofexidine
Effects
Effects described from scientific sources. Individual experiences vary.
Dosage
Individual sensitivity varies. Not a dosage recommendation.
Duration
Risks & Warnings
Warnings
- Severe cardiovascular diseases
- Hypotension
- Allergy to lofexidine
Known Risks
- medium
- Mögliche Nebenwirkungen umfassen Hypotonie, Sedierung und Bradykardie.
Safer Use
- Start at a low dose.
- Regular monitoring of blood pressure.
- Avoid alcohol and other sedating substances.
Harm reduction tips do not replace medical advice.
Known Interactions
- Antihypertensives
- Sedatives
- Opioids
This list is not exhaustive. Interactions can have unpredictable effects.
Legal Status
Not legal advice. Status may change.
Entdecken
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