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2-(2,5-dimethoxy-4-nitro-phenyl)ethyl-o-anisyl-amine
25N-NBOMe is a synthetic psychedelic phenethylamine from the NBOMe series, primarily acting as a potent 5-HT2A receptor agonist. It is known for its strong hallucinogenic effects, which can be associated with significant health risks.
Class
Not clearly classified yet
Pharmacological context
Mechanism
As a potent 5-HT2A receptor agonist, 25N-NBOMe induces its effects...
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
Interpret risks carefully
Condensed from structured notes
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Designations
IUPAC: 2-(2,5-dimethoxy-4-nitro-phenyl)ethyl-o-anisyl-amine
Receptor Profile
Der 5-HT2A-Rezeptor ist ein Serotonin-Rezeptor der Klasse Gq-gekoppelter GPCRs. Er ist der primäre molekulare Angriffspunkt klassischer Psychedelika und spielt eine Rolle bei Kognition und Wahrnehmung.
Der 5-HT2C-Rezeptor ist ein Gq/11-gekoppelter Serotoninrezeptor, der an der Regulation von Appetit, Stimmung und Angst beteiligt ist. Er wird von verschiedenen Psychedelika als sekundäres Ziel aktiviert und moduliert dopaminerge Signalwege.
Synapedia Evidence
Effects & Pharmacology is partially translated. Some details are still being expanded.
As a potent 5-HT2A receptor agonist, 25N-NBOMe induces its effects through modulation of serotonergic signaling in the brain.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Risks & Harm Reduction is partially translated. Some details are still being expanded.
Risks
Summary
Geringes akutes Toxizitätsrisiko bei typischen Dosen. Set und Setting entscheidend — Risiko für angstbesetzte Erfahrungen (Bad Trips), Depersonalisation und in seltenen Fällen anhaltende Wahrnehmungsstörungen (HPPD). Kein physisches Abhängigkeitspotenzial.
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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