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2-[[2-(4-chloro-2,5-dimethoxy-phenyl)ethylamino]methyl]phenol
25C-NBOH is a synthetic psychedelic phenethylamine that acts as a potent agonist at the 5-HT2A receptor. It belongs to the NBOH family and is structurally related to 2C-C. The substance induces visual and sensory alterations, with effects strongly dependent on dosage.
Class
Not clearly classified yet
Pharmacological context
Mechanism
25C-NBOH functions primarily as an agonist at the 5-HT2A receptor,...
Short read on known pharmacology
Interactions
No curated pairs visible
Curated visible combinations
Risk theme
Interpret risks carefully
Condensed from structured notes
Translation in progress
The German version has more complete content. This English page is being expanded; safety-critical risk and interaction sections may still appear while translation continues.
Receptor Targets
Mechanism of Action
Designations
IUPAC: 2-[[2-(4-chloro-2,5-dimethoxy-phenyl)ethylamino]methyl]phenol
Receptor Profile
Der 5-HT2A-Rezeptor ist ein Serotonin-Rezeptor der Klasse Gq-gekoppelter GPCRs. Er ist der primäre molekulare Angriffspunkt klassischer Psychedelika und spielt eine Rolle bei Kognition und Wahrnehmung.
Der 5-HT2C-Rezeptor ist ein Gq/11-gekoppelter Serotoninrezeptor, der an der Regulation von Appetit, Stimmung und Angst beteiligt ist. Er wird von verschiedenen Psychedelika als sekundäres Ziel aktiviert und moduliert dopaminerge Signalwege.
Synapedia Evidence
Effects & Pharmacology is partially translated. Some details are still being expanded.
25C-NBOH functions primarily as an agonist at the 5-HT2A receptor, which is implicated in the modulation of mood, perception, and cognition.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Dosage & Duration translation in progress
English prose is being expanded. The German version currently has more detail.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks & Harm Reduction translation in progress
English prose is being expanded. Safety-critical structured data may still be shown when available.
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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