Substance Comparison
Methamphetamin stands out with markedly stronger addiction risk. Methamphetamin stands out with markedly stronger stimulation. Methamphetamin stands out with markedly stronger body load. SSRI leans slightly higher in sedation.
Despite belonging to different classes, these substances share receptor activity at SERT, which may produce overlapping effects.
Methamphetamin has significantly higher addiction risk
Methamphetamin has significantly higher stimulation
Methamphetamin has significantly higher body load
SSRI has somewhat higher sedation
| Methamphetamin | SSRI | |
|---|---|---|
| Class | Stimulanzien | Antidepressiva |
| Risk Level | high | low |
| Mechanisms | DAT-Umkehrtransport, NET-Umkehrtransport, SERT-Umkehrtransport, TAAR1-Agonist | Selektive Serotonin-Wiederaufnahmehemmung |
| Receptors | DAT, NET, SERT, TAAR1 | SERT |
| Effects | Euphorie, Erhöhte Wachsamkeit, Appetitlosigkeit, Schlaflosigkeit, Angst | — |
| Evidence | — | — |
No harm reduction data available
No harm reduction data available
Evidence: not assessed · Sources: 2
Evidence: not assessed · Sources: 2