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Δ9-Tetrahydrocannabinol (THC) is the primary psychoactive compound of the cannabis plant. It primarily acts as an agonist at the cannabinoid receptors CB1 and CB2, leading to characteristic effects such as euphoria, altered perception, and pain relief. THC possesses both sedative and anti-inflammatory properties. The substance can pose psychological and physical risks when misused.
Receptor Targets
Mechanism of Action
Designations
IUPAC: THC (Δ9-THC)
Legal Status
Legal status not verified by official sources. Please check current legislation independently.
Information without guarantee. Not legal advice.
Substance Fingerprint
Pharmacological profile based on receptor binding, mechanism of action, and substance class. Limited data — interpret profile with caution.
Synapedia Evidence
Δ9-THC primarily acts as an agonist at cannabinoid receptors, particularly CB1 and CB2. These receptors are part of the endocannabinoid system, which plays a role in the regulation of pain, mood, and appetite.
Known Effects
Individual effects may vary significantly. These are pharmacologically documented effects.
Total duration 4-8 hours (oral), 2-4 hours (smoked/vaporized)
Peak
1-3 hours (oral), 30-60 minutes (smoked/vaporized)
Onset
30-90 minutes (oral), 2-10 minutes (smoked/vaporized)
Total duration
4-8 hours (oral), 2-4 hours (smoked/vaporized)
After effects
1-3 hours
Start low. Individual sensitivity varies.
Dose sensitivity varies greatly between individuals. Body weight, tolerance, route of administration, combinations, and pre-existing conditions significantly affect outcomes. These figures are not dosing recommendations — they describe reported ranges, not safe amounts.
Risks
Evidence
strong
Neurotoxicity
possible
Safer Use
The risks listed may be incomplete. Especially for research chemicals and rare substances, available data is limited.
Interaction details from the knowledge layer are still being translated.
Interaction data is based on known mechanisms. Unknown or rare interactions are possible and may be life-threatening.
Based on substance class, receptors, mechanisms, and effect profile.
This information is for scientific and harm-reduction purposes only. It does not constitute medical advice.
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