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tca and Tramadol — Interaction & Risk | Synapedia

Interaction Checker

tca & Tramadol

Hohes Risiko: Serotoninsyndrom, Krampfanfälle und Kardiotoxizität

High Risk

Curated Data

Risk Assessment

High Risk

Tramadol und TCA teilen serotonerge Mechanismen und senken beide die Krampfschwelle. Die Kombination kann ein Serotoninsyndrom, Krampfanfälle und über die TCA-bedingte Natriumkanalblockade auch kardiale Arrhythmien auslösen.