Laden…
Critical Risk: Risk of severe serotonin syndrome
DXM (dextromethorphan) has serotonergic activity, and MAO inhibitors block the breakdown of serotonin. Taken together they can cause a dangerous accumulation of serotonin and a high risk of severe serotonin syndrome, which can present with high body temperature, muscle rigidity, autonomic instability and altered consciousness.
Mechanism data is language-neutral pharmacological notation.
This page is based on curated pharmacological data and/or community signals. It is intended for scientific education and harm reduction only. It does not replace professional medical advice. Not all interactions are covered — always consult a healthcare professional when in doubt. In emergencies, call your local emergency number.