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DMT and maoi — Interaction & Risk | Synapedia

Interaction Checker

DMT & maoi

Potenziell lebensbedrohlich: Massive serotonerge Überflutung

High Risk

Curated Data

Risk Assessment

High Risk

DMT wird normalerweise durch MAO-A im Darm rasch abgebaut und ist oral kaum wirksam. MAO-Inhibitoren machen DMT oral bioverfügbar (Ayahuasca-Prinzip) und verlängern die Wirkung drastisch. Bei pharmazeutischen MAOI ist die MAO-Hemmung stärker und unkontrollierbarer als bei natürlichen Harman-Alkaloiden, was zu gefährlich hohen Serotonin-Spiegeln führen kann.