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Tranylcypromine

Tranylcypromine is an irreversible monoamine oxidase inhibitor used for the treatment of depression. It increases the concentration of monoamines such as serotonin, norepinephrine, and dopamine in the synaptic cleft. Due to its mechanism of action, interactions with certain foods and medications must be considered. The substance can cause side effects such as increased blood pressure and sleep disturbances.

Antidepressiva
Antidepressiva
Monoaminoxidase A
Monoaminoxidase B

Mechanism of Action

Names / Identifiers

IUPAC: Tranylcypromine

tranylcypromine
dl-Tranylcypromine
Transamine
Racemic Tranylcypromine
SKF 385
Jatrosom
Parnitene
Tranilcipromina
Tranylcyprominum
NSC80664

Mechanism of Action

Tranylcypromin wirkt als irreversibler Hemmer der Monoaminoxidase, was zu einer erhöhten Verfügbarkeit von Neurotransmittern wie Serotonin, Noradrenalin und Dopamin im synaptischen Spalt führt.

Effects

Antidepressiv
Angstlösend
Stimmungsaufhellend
Energie steigernd
Appetitzügelnd

Effects described from scientific sources. Individual experiences vary.

Dosage

Safety NoteIndividual variation, start with a low dose, no medical advice.

Individual sensitivity varies. Not a dosage recommendation.

Duration

Peak2-4 hours
NotesEffects may vary from person to person.
Onset1-2 hours
Total24 hours
After EffectsVariable

Risks & Warnings

Warnings

  • Severe liver disease
  • Cardiovascular diseases
  • Concurrent use of certain antidepressants

Known Risks

  • medium
  • Kann zu hypertensiven Krisen führen, insbesondere bei gleichzeitiger Einnahme bestimmter Nahrungsmittel oder Medikamente.

Safer Use

  • Avoidance of tyramine-rich foods.
  • Regular medical monitoring.
  • Inform about possible interactions.

Harm reduction tips do not replace medical advice.

Known Interactions

  • Selective serotonin reuptake inhibitors (SSRIs)
  • Tyramine-rich foods
  • Other MAO inhibitors

This list is not exhaustive. Interactions can have unpredictable effects.

Legal Status

ATVerschreibungspflichtig
CHVerschreibungspflichtig
DEVerschreibungspflichtig
USVerschreibungspflichtig
NotesTranylcypromin ist in vielen Ländern als Antidepressivum zugelassen.

Not legal advice. Status may change.