Translated automatically – community improvements welcome.
Baclofen
Baclofen is a centrally acting muscle relaxant that acts as a selective GABA-B receptor agonist. It is primarily used for the treatment of muscle spasticity and also shows potential in supporting addiction disorders. The substance affects neuronal excitability by inhibiting neurotransmitter release. Side effects may include sedation and muscle weakness.
Mechanism of Action
- GABA-B agonist
Names / Identifiers
IUPAC: Baclofen
Mechanism of Action
Baclofen wirkt als Agonist an den GABA-B-Rezeptoren, was zu einer Hemmung der neuronalen Erregung und einer Muskelrelaxation führt.
Effects
Effects described from scientific sources. Individual experiences vary.
Dosage
Individual sensitivity varies. Not a dosage recommendation.
Duration
Risks & Warnings
Warnings
- Pregnancy
- Breastfeeding
- Severe renal impairment
Known Risks
- medium
- Mögliche Nebenwirkungen umfassen Schläfrigkeit, Schwindel und Übelkeit.
Safer Use
- Start at a low dose.
- Be aware of interactions with other medications.
Harm reduction tips do not replace medical advice.
Known Interactions
- Alcohol
- Benzodiazepines
This list is not exhaustive. Interactions can have unpredictable effects.
Legal Status
Not legal advice. Status may change.
Entdecken
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